CRISPR Cas9 - Gene Regulation with dCas9
abmgood.com
CRISPR Cas9 - Gene Regulation with dCas9
In this article, we'll explain how the enzymatically dead Cas9 (dCas9) protein can be used for transcriptional modulation. You'll learn about dCas9 modifications for gene activatio (dCas9-SAM), repression (dCas9-KRAB), epigenetic editing (dCas9-p300, dCas9-LSD1), and the modulation of DNA methylation (dCas9-TET1CD, dCas9-DNMT3A).
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